Fgfr2 (Fibroblast growth factor receptor 2) – MGI gene detail
Description: Fgfr2 is expressed in the palatal epithelium along the AP axis throughout development, including the oral and nasal epithelia and in the MEE. It is also expressed in the nasal mesenchyme at E13.5 only in the posterior region of the palatal shelf.
Source:
Snyder-Warwick et al. (2010) Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate. PNAS 107(6): 2515-20.
Porntaveetus et al. (2010) Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr. Patterns 10(4-5): 193-8.