Category Archives: Transcription factors

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Dlx5 gene expression

Dlx5 (Distal-less homeobox 5) – MGI gene detail Description: Dlx5 is expressed in the nasal mesenchyme along the AP axis of the E13.5 palatal shelf. Source: Han et al., 2009 Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of … Continue reading

Posted in Anterior region, Mesenchyme, Mouse, Nasal region, Posterior region, Transcription factors |

Gli1 gene expression

Gli1 – MGI gene detail Description: Gli1 is expressed in the oral mesenchyme and oral epithelium along the AP axis at E13.5. At E14.5, expression is restricted to the oral mesenchyme of the anterior region of the palate. Sources: Han et … Continue reading

Posted in Anterior region, Epithelium, Mesenchyme, Mouse, Oral epithelium, Oral region, Posterior region, Transcription factors |

Irf6 gene expression

Irf6 (Interferon regulatory factor 6) – MGI gene detail Description: Irf6 is expressed in the palatal epithelium along the AP axis throughout development, including the oral and nasal epithelia and in the MEE from E14.5 to E15.5. Source: Immunofluorescence. Unpublished data … Continue reading

Posted in Epithelium, Midline epithelium, Mouse, Nasal epithelium, Oral epithelium, Transcription factors |

Msx1 gene expression

Msx1 (Msh homeobox 1) – MGI gene detail   Description: Msx1 is expressed in the mesenchyme of the anterior region of the developing palate, on both nasal and oral sides. Sources: Zhang et al. (2002) Rescue of cleft palate in Msx1-deficient … Continue reading

Posted in Anterior region, Mesenchyme, Mouse, Nasal region, Oral region, Transcription factors |

Osr2 gene expression

Osr2 (Odd-skipped related 2) – MGI gene detail Description: Osr2 is expressed in the mesenchyme of the anterior region of the developing palate and it is restricted to the oral side. Source: Lan et al. (2004) Odd-skipped related 2 (Osr2) encodes a key … Continue reading

Posted in Anterior region, Mesenchyme, Mouse, Oral region, Transcription factors |

P-SMAD1/5/8

Phospho-SMAD 1/5/8 – MGI gene detail for Smad1, 5, 8 Description: Activation of BMP signaling is observed in the nasal mesenchyme of the palatal shelves at E13.5 and E14.5 along the AP axis. A few P-SMAD1/5/8-positive cells in the oral … Continue reading

Posted in Anterior region, Epithelium, Intracellular molecules, Mesenchyme, Mouse, Nasal epithelium, Nasal region, Oral epithelium, Posterior region, Transcription factors |

Pitx2 gene expression

Pitx2 (Paired-like homeodomain transcription factor 2 / Pituitary homeobox 2) – MGI gene detail Description: At E13.5, Pitx2 is expressed in the palatal epithelium along the AP axis. At E14.5, Pitx2 is expressed in both the epithelium and the osteogenic mesenchyme … Continue reading

Posted in Anterior region, Epithelium, Mesenchyme, Midline epithelium, Mouse, Oral epithelium, Oral region, Osteogenic mesenchyme, Posterior region, Transcription factors |

Runx2 gene expression

Runx2 (Runt-related transcription factor 2) – MGI gene detail Description: At E13.5 and E15.5, Runx2 is expressed in the osteogenic mesenchyme along the AP axis. Sources: Yamashiro et al. (2002) Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone … Continue reading

Posted in Anterior region, Mesenchyme, Mouse, Oral region, Osteogenic mesenchyme, Posterior region, Transcription factors |

Shox2 gene expression

Shox2 (Short stature homeobox gene 2) – MGI gene detail Description: Shox2 is expressed in the mesenchyme of the anterior region of the developing palate, on both nasal and oral sides. Source: Yu et al. (2005) Shox2-deficient mice exhibit a rare … Continue reading

Posted in Anterior region, Mesenchyme, Mouse, Nasal region, Oral region, Transcription factors |

Sox2 gene expression

Sox2 (SRY-box containing 2) – MGI gene detail Description: Sox2 is expressed in the palatal epithelium along the AP axis throughout development, including the oral and nasal epithelia and in the MEE from E14.5 to E15.5. Source: Immunofluorescence and Sox2-GFP knockin mice. Unpublished … Continue reading

Posted in Epithelium, Midline epithelium, Mouse, Nasal epithelium, Oral epithelium, Transcription factors |

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