December 2011 – Craniofacial Central

P-SMAD1/5/8

Categories: Anterior region, Epithelium, Intracellular molecules, Mesenchyme, Mouse, Nasal epithelium, Nasal region, Oral epithelium, Posterior region, Transcription factors

Phospho-SMAD 1/5/8 – MGI gene detail for Smad1, 5, 8 Description: Activation of BMP signaling is observed in the nasal mesenchyme of the palatal shelves at E13.5 and E14.5 along the AP axis. A few P-SMAD1/5/8-positive cells in the oral and nasal epithelia are also detectable (not depicted here). Source: Han et al. (2009) Indirect modulation…Continue Reading P-SMAD1/5/8

Pitx2 gene expression

Categories: Anterior region, Epithelium, Mesenchyme, Midline epithelium, Mouse, Oral epithelium, Oral region, Osteogenic mesenchyme, Posterior region, Transcription factors

Pitx2 (Paired-like homeodomain transcription factor 2 / Pituitary homeobox 2) – MGI gene detail Description: At E13.5, Pitx2 is expressed in the palatal epithelium along the AP axis. At E14.5, Pitx2 is expressed in both the epithelium and the osteogenic mesenchyme along the AP axis. Source: Iwata et al. (2012) Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2)…Continue Reading Pitx2 gene expression