Genotype | Wnt1-Cre;Tgfbr2fl/fl |
Symbol (MGI) | Tgfbr2tm1.2Hlm |
Known defects | Cleft palate, bone defects, small tongue |
Known human diseases | Loeys-Dietz Syndrome |
Histology | E18.5 |
SEM | E18.5 |
μCT | E18.5: soft – hard |
3D μCT | E18.5: soft – hard |
μMRI | E18.5: soft |
Gene expression analysis | E14.5 |
Protein expression analysis | |
References | Ito Y et al., Development 2003 Sasaki T et al., Development 2006 Oka K et al., Dev Biol 2007 Oka K et al., Dev Biol 2008 Iwata J et al., J Biol Chem 2010 Iwata J et al., J Clin Invest 2012 Iwata J et al., J Biol Chem 2012 |