GenotypeWnt1-Cre;Tgfbr2fl/fl
Symbol (MGI)Tgfbr2tm1.2Hlm
Known defectsCleft palate, bone defects, small tongue
Known human diseasesLoeys-Dietz Syndrome
HistologyE18.5
SEME18.5
μCTE18.5: soft – hard
3D μCTE18.5: soft – hard
μMRIE18.5: soft
Gene expression analysisE14.5
Protein expression analysis 
ReferencesIto Y et al., Development 2003
Sasaki T et al., Development 2006
Oka K et al., Dev Biol 2007
Oka K et al., Dev Biol 2008
Iwata J et al., J Biol Chem 2010
Iwata J et al., J Clin Invest 2012
Iwata J et al., J Biol Chem 2012