Category Archives: MesenchymeNewer posts →
Phospho-SMAD 1/5/8 – MGI gene detail for Smad1, 5, 8 Description: Activation of BMP signaling is observed in the nasal mesenchyme of the palatal shelves at E13.5 and E14.5 along the AP axis. A few P-SMAD1/5/8-positive cells in the oral … Continue reading
Pitx2 (Paired-like homeodomain transcription factor 2 / Pituitary homeobox 2) – MGI gene detail Description: At E13.5, Pitx2 is expressed in the palatal epithelium along the AP axis. At E14.5, Pitx2 is expressed in both the epithelium and the osteogenic mesenchyme … Continue reading
Runx2 (Runt-related transcription factor 2) – MGI gene detail Description: At E13.5 and E15.5, Runx2 is expressed in the osteogenic mesenchyme along the AP axis. Sources: Yamashiro et al. (2002) Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone … Continue reading
Shox2 (Short stature homeobox gene 2) – MGI gene detail Description: Shox2 is expressed in the mesenchyme of the anterior region of the developing palate, on both nasal and oral sides. Source: Yu et al. (2005) Shox2-deficient mice exhibit a rare … Continue reading
Tgfbr2 (TGF-Beta receptor 2) – MGI gene detail Description: Tgfbr2 is expressed in both epithelium and mesenchyme along the oral-nasal and anterior-posterior axes at E13.5. Data at other stages is not available. Source: Radioactive in situ hybridization. Unpublished data from Chai’s lab.