Wildtype mice:
- E10.5 through E14.5 distal and proximal portions of the mandible and maxilla – perform customized analyses in our interactive web app
Mutant mouse models and associated controls:
- E11.5 mice with conditional inactivation of Erk2 in the cranial neural crest – mandible
- E12.5 mice with conditional inactivation of Erk2 in the cranial neural crest – mandible
- E13.5 mice with conditional inactivation of Alk5 in the cranial neural crest – palate
- E13.5 mice with conditional inactivation of Erk2 in the cranial neural crest – tongue
- E13.5 mice with conditional inactivation of Erk2 in the cranial neural crest – palate
- E13.5 mice with conditional inactivation of Smad4 in the Myf5-expressing lineage – tongue
- E13.5 mice with conditional inactivation of Tgfbr2 in the cranial neural crest – tongue
- E14.5 mice with conditional inactivation of Erk2 in the cranial neural crest – palate
- E14.5 mice with conditional inactivatoin of Erk2 in the cranial neural crest – tongue
- E14.5 Msx1-/- mice – palate and mandible
- E14.5 mice with conditional inactivation of Tgfrb2 in the cranial neural crest – palate
- E14.5 mice with conditional inactivation of Tgfbr2 and conditional haploinsufficiency of Alk5 in the cranial neural crest – palate
All of our data are available for download at FaceBase.org