Fgf7 (Fibroblast growth factor 7) – MGI gene detail

Description: At E12.5 and E13.5, Fgf7 is expressed in the mesenchyme along the AP axis and it is restricted to the nasal side. At E14.5, Fgf7 is expressed along the AP and ON axes of the palate.

Sources: 

Han et al., 2009 Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of palate and rescues cleft palate in Msx1-null mice.Development 136(24):4225-33.

Rice et al., 2004 Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palateJ. Clin. Invest. 113(12):1692-700.