Class III cleft palate

Class III: Palatal shelves fail to meet at the midline

Complete cleft of secondary palate

Partial cleft of secondary palate: anterior

  • K14-Cre;Alk5fl/fl
  • K14-Cre;Tgfbr2fl/fl
  • Shox2-/-
  • Wnt1-Cre;Shox2fl/fl
Partial cleft of secondary palate: posterior / cleft soft palate

  • K14-Cre;Alk5fl/fl
  • K14-Cre;Tgfbr2fl/fl
  • Tbx1-/-